BAIT
SLC1A2
1700091C19Rik, 2900019G14Rik, AI159670, Eaat2, GLT-1, GLT1, MGLT1, RP23-163L4.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
GO Process (17)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [ISO]
- L-glutamate transmembrane transport [IMP, ISO]
- L-glutamate transport [IDA, IMP, ISO]
- adult behavior [IMP]
- cellular response to extracellular stimulus [IMP]
- multicellular organism growth [IMP]
- multicellular organismal aging [IMP]
- nervous system development [IMP]
- positive regulation of glucose import [IMP]
- response to amino acid [IMP]
- response to drug [IMP]
- response to light stimulus [IMP]
- response to wounding [IMP]
- sodium ion transmembrane transport [ISO]
- telencephalon development [IMP]
- visual behavior [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
INPPL1
51C, SHIP2
inositol polyphosphate phosphatase-like 1
GO Process (19)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- actin filament organization [ISO]
- cellular lipid metabolic process [IMP]
- dephosphorylation [ISO]
- endochondral ossification [ISO]
- endocytosis [ISO]
- glucose metabolic process [IMP]
- inositol trisphosphate metabolic process [ISO]
- negative regulation of DNA replication [ISO]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of cell proliferation [IDA]
- negative regulation of gene expression [IMP]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of insulin-like growth factor receptor signaling pathway [ISO]
- negative regulation of neuron projection development [ISO]
- negative regulation of platelet-derived growth factor receptor signaling pathway [ISO]
- phosphatidylinositol biosynthetic process [IMP]
- post-embryonic development [IMP]
- response to insulin [IMP]
- ruffle assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.
Dopamine (DA) transporters (DATs) are regulated by trafficking and modulatory processes that probably rely on stable and transient interactions with neighboring proteins and lipids. Using proximity-dependent biotin identification (BioID), we found novel potential partners for DAT, including several membrane proteins, such as the transmembrane chaperone 4F2hc, the proteolipid M6a and a potential membrane receptor for progesterone (PGRMC2). We also detected ... [more]
Cell Mol Life Sci Dec. 01, 2021; 78(23);7733-7756 [Pubmed: 34709416]
Throughput
- Low Throughput
Additional Notes
- BioID
Curated By
- BioGRID