UBP3
Gene Ontology Biological Process
Gene Ontology Molecular Function
PYP1
Gene Ontology Biological Process
- inactivation of MAPK activity [IMP]
- negative regulation of G2/M transition of mitotic cell cycle [IMP]
- negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [IMP]
- negative regulation of transcription by glucose [IMP]
- peptidyl-tyrosine dephosphorylation [IDA, ISS]
- peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
The extent by which different cellular components generate phenotypic diversity is an ongoing debate in evolutionary biology that is yet to be addressed by quantitative comparative studies. We conducted an in vivo mass-spectrometry study of the phosphoproteomes of three yeast species (Saccharomyces cerevisiae, Candida albicans, and Schizosaccharomyces pombe) in order to quantify the evolutionary rate of change of phosphorylation. We ... [more]
Throughput
- High Throughput
Ontology Terms
- phenotype: colony size (APO:0000063)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PYP1 UBP3 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -3.4921 | BioGRID | 762258 | |
| UBP3 PYP1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -3.4921 | BioGRID | 760993 |
Curated By
- BioGRID