BAIT
TRIB1
C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1
tribbles pseudokinase 1
GO Process (10)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- JNK cascade [IMP]
- negative regulation of lipopolysaccharide-mediated signaling pathway [IMP]
- negative regulation of protein kinase activity [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IMP, ISS]
- negative regulation of smooth muscle cell migration [IMP]
- negative regulation of smooth muscle cell proliferation [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- protein phosphorylation [TAS]
- regulation of MAP kinase activity [IDA]
- response to lipopolysaccharide [IMP, ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
KLC2
kinesin light chain 2
GO Process (3)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.
Autophagy-related protein 9 (ATG9) is a transmembrane protein component of the autophagy machinery that cycles between the trans-Golgi network (TGN) in the perinuclear area and other compartments in the peripheral area of the cell. In mammalian cells, export of the ATG9A isoform from the TGN into ATG9A-containing vesicles is mediated by the adaptor protein 4 (AP-4) complex. However, the mechanisms ... [more]
Mol Biol Cell Dec. 01, 2020; 32(21);ar25 [Pubmed: 34432492]
Throughput
- Low Throughput
Curated By
- BioGRID