BAIT

RUSC2

Iporin
RUN and SH3 domain containing 2
GO Process (0)
GO Function (2)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

KLC1

KLC, KNS2, KNS2A, RP11-73M18.7
kinesin light chain 1
Alzheimer's Disease Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.

Guardia CM, Jain A, Mattera R, Friefeld A, Li Y, Bonifacino JS

Autophagy-related protein 9 (ATG9) is a transmembrane protein component of the autophagy machinery that cycles between the trans-Golgi network (TGN) in the perinuclear area and other compartments in the peripheral area of the cell. In mammalian cells, export of the ATG9A isoform from the TGN into ATG9A-containing vesicles is mediated by the adaptor protein 4 (AP-4) complex. However, the mechanisms ... [more]

Mol Biol Cell Dec. 01, 2020; 32(21);ar25 [Pubmed: 34432492]

Throughput

  • Low Throughput

Curated By

  • BioGRID