BAIT
XE7
CG2179, Dmel\CG2179, l(3)02248, Dmel_CG2179
CG2179 gene product from transcript CG2179-RD
GO Process (2)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Drosophila melanogaster
PREY
DREF
CG5838, DmDREF, Dmel\CG5838, Dmel_DREF, dDREF, p80, p80/DREF, Dmel_CG5838
DNA replication-related element factor
GO Process (21)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- DNA endoreduplication [IMP]
- DNA replication [TAS]
- chaeta development [IMP]
- compound eye development [IMP]
- compound eye morphogenesis [IMP]
- dendrite morphogenesis [IMP]
- mitochondrial DNA replication [TAS]
- mitotic spindle organization [IMP]
- neurogenesis [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- protein autophosphorylation [ISS]
- protein phosphorylation [ISS]
- regulation of DNA biosynthetic process [IDA]
- regulation of apoptotic process [IDA]
- regulation of cell cycle [NAS]
- regulation of cell proliferation involved in compound eye morphogenesis [IDA]
- regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of transcription, DNA-templated [TAS]
- sensory organ precursor cell division [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IPI]
- calcium ion binding [ISS]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription regulatory region sequence-specific DNA binding [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IPI]
- calcium ion binding [ISS]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription regulatory region sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID