BAIT
FOLR1
FBP, FOLR
folate receptor 1 (adult)
GO Process (2)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS9
S9, XXbac-BCX105G6.6
ribosomal protein S9
GO Process (15)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- positive regulation of cell proliferation [IMP]
- positive regulation of translational fidelity [IBA]
- translation [IC, IMP, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Folate receptor ? increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer.
The main function of folate receptor ? (FOLR?) has been considered to mediate intracellular folate uptake and induce tumor cell proliferation. Given the broad spectrum of expression among malignant tumors, including gastric cancer (GC) but not in normal tissue, FOLR? represents an attractive target for tumor-selective drug delivery. However, the efficacy of anti-FOLR? monoclonal antibodies (mAbs) has not been proved ... [more]
Clin Transl Med Dec. 01, 2020; 11(6);e454 [Pubmed: 34185411]
Throughput
- Low Throughput
Curated By
- BioGRID