BAIT

ILDR2

C1orf32, dJ782G3.1, RP4-782G3.2
immunoglobulin-like domain containing receptor 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

HSD17B12

KAR, SDR12C1
hydroxysteroid (17-beta) dehydrogenase 12
GO Process (4)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression.

Watanabe K, Nakayama K, Ohta S, Tago K, Boonvisut S, Millings EJ, Fischer SG, LeDuc CA, Leibel RL, Iwamoto S

A diabetes susceptibility gene, immunoglobulin-like domain containing receptor 2 (Ildr2), encodes a transmembrane protein localized to the endoplasmic reticulum membrane that is closely related to hepatic lipid metabolism. The livers of ob/ob mice in which Ildr2 is transiently overexpressed are relieved of hepatic steatosis. However, the molecular mechanisms through which ILDR2 affects these changes in hepatic lipid metabolism remain unknown. ... [more]

Biochem Biophys Res Commun Dec. 02, 2015; 477(4);712-716 [Pubmed: 27353377]

Throughput

  • Low Throughput

Curated By

  • BioGRID