BAIT

FXR1

FXR1P
fragile X mental retardation, autosomal homolog 1
GO Process (2)
GO Function (3)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

CPSF6

CFIM, CFIM68, HPBRII-4, HPBRII-7
cleavage and polyadenylation specific factor 6, 68kDa
GO Process (3)
GO Function (4)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA.

Deng M, Wang N, Li Z, Chen R, Duan J, Peng Y, Wu Z, Zhang Z, Jiang L, Zheng X, Xie D, Wei W, Liu Z, Zhou F

RNA-binding proteins (RBPs) are key regulators of gene expression. RBP dysregulation is reported to play essential roles in tumorigenesis. However, the role of RBPs in urothelial carcinoma of the bladder (UCB) is only starting to be unveiled. Here, we comprehensively assessed the mRNA expression landscape of 104 RBPs from two independent UCB cohorts, Sun Yat-sen University Cancer Center (SYSUCC) and ... [more]

Cell Death Dis Dec. 22, 2021; 13(2);170 [Pubmed: 35194031]

Throughput

  • Low Throughput

Curated By

  • BioGRID