BAIT
PCBP1
HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
poly(rC) binding protein 1
GO Process (3)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP5B
ATPMB, ATPSB, HEL-S-271
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
GO Process (11)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- ATP biosynthetic process [IMP]
- ATP catabolic process [IDA]
- angiogenesis [IMP]
- cellular metabolic process [TAS]
- generation of precursor metabolites and energy [NAS]
- mitochondrial ATP synthesis coupled proton transport [IC, TAS]
- osteoblast differentiation [IDA]
- proton transport [IMP]
- regulation of intracellular pH [IMP]
- respiratory electron transport chain [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell surface [IDA]
- extracellular vesicular exosome [IDA]
- membrane [IDA]
- mitochondrial matrix [NAS, TAS]
- mitochondrial membrane [IDA]
- mitochondrial nucleoid [IDA]
- mitochondrial proton-transporting ATP synthase complex [IDA]
- mitochondrial proton-transporting ATP synthase, catalytic core [NAS]
- mitochondrion [IDA]
- nucleus [IDA]
- plasma membrane [IDA]
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.
The epithelial to mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metastasis to distant organs, requires coordinated transcriptional and post-transcriptional control of gene expression. The tumor-suppressive RNA binding protein, hnRNP-E1, regulates splicing and translation of EMT-associated transcripts and it is thought that it plays a major role in the control of epithelial cell plasticity during ... [more]
Oncogene Dec. 01, 2021; 41(12);1679-1690 [Pubmed: 35102251]
Throughput
- High Throughput
Additional Notes
- miniTurbo BioID assay
Curated By
- BioGRID