BAIT

KIAA1715

LNP, LNP1, Ul, ulnaless
KIAA1715
GO Process (1)
GO Function (0)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

AGL

GDE
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Co-adaptor driven assembly of a CUL3 E3 ligase complex.

Akopian D, McGourty CA, Rape M

Cullin-RING E3 ligases (CRLs) are essential ubiquitylation enzymes that combine a catalytic core built around cullin scaffolds with ?300 exchangeable substrate adaptors. To ensure robust signal transduction, cells must constantly form new CRLs by pairing substrate-bound adaptors with their cullins, but how this occurs at the right time and place is still poorly understood. Here, we show that formation of ... [more]

Mol Cell Dec. 03, 2021; 82(3);585-597.e11 [Pubmed: 35120648]

Throughput

  • High Throughput

Curated By

  • BioGRID