BAIT

TUBB3

CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
tubulin, beta 3 class III
GO Process (4)
GO Function (1)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

FKBP5

AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10, RP3-340B19.6
FK506 binding protein 5
Alzheimer's Disease Project
Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.

Qiu B, Zhong Z, Righter S, Xu Y, Wang J, Deng R, Wang C, Williams KE, Ma YY, Tsechpenakis G, Liang T, Yong W

FK506-binding protein 51 (encoded by Fkpb51, also known as Fkbp5) has been associated with stress-related mental illness. To investigate its function, we studied the morphological consequences of Fkbp51 deletion. Artificial Intelligence-assisted morphological analysis revealed that male Fkbp51 knock-out (KO) mice possess more elongated dentate gyrus (DG) but shorter hippocampal height in coronal sections when compared to WT. Primary cultured Fkbp51 ... [more]

Cell Mol Life Sci Mar. 04, 2022; 79(3);175 [Pubmed: 35244772]

Throughput

  • Low Throughput

Curated By

  • BioGRID