BAIT
RAP2C
RAP2C, member of RAS oncogene family
GO Process (5)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB40B
RAR, SEC4L
RAB40B, member RAS oncogene family
GO Process (7)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration.
Cell migration is a complex process that involves coordinated changes in membrane transport and actin cytoskeleton dynamics. Ras-like small monomeric GTPases, such as Rap2, play a key role in regulating actin cytoskeleton dynamics and cell adhesions. However, how Rap2 function, localization, and activation are regulated during cell migration is not fully understood. We previously identified the small GTPase Rab40b as ... [more]
J Cell Biol Dec. 04, 2021; 221(4); [Pubmed: 35293963]
Throughput
- Low Throughput
Curated By
- BioGRID