BAIT
GJA1
AVSD3, CMDR, CX43, GJAL, HLHS1, HSS, ODDD
gap junction protein, alpha 1, 43kDa
GO Process (11)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- atrial cardiac muscle cell action potential [TAS]
- cell communication by electrical coupling [IDA]
- cell-cell signaling [TAS]
- gap junction assembly [TAS]
- heart development [TAS]
- ion transmembrane transport [TAS]
- membrane organization [TAS]
- muscle contraction [TAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- signal transduction [IMP]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISS]
- Golgi membrane [TAS]
- Golgi-associated vesicle membrane [TAS]
- endoplasmic reticulum membrane [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- gap junction [IDA, ISS]
- integral component of plasma membrane [TAS]
- intercalated disc [IDA, ISS]
- membrane raft [ISS]
- plasma membrane [ISS, TAS]
Homo sapiens
PREY
APOB
FLDB, LDLCQ4
apolipoprotein B
GO Process (17)
GO Function (6)
GO Component (22)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cholesterol homeostasis [IMP]
- cholesterol metabolic process [IMP]
- cholesterol transport [IMP]
- leukocyte migration [TAS]
- lipoprotein metabolic process [TAS]
- low-density lipoprotein particle clearance [IMP]
- low-density lipoprotein particle remodeling [IMP]
- phototransduction, visible light [TAS]
- positive regulation of cholesterol storage [IDA]
- positive regulation of lipid storage [IDA]
- positive regulation of macrophage derived foam cell differentiation [IDA]
- receptor-mediated endocytosis [TAS]
- response to virus [IEP]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
- very-low-density lipoprotein particle assembly [IC]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- actin cytoskeleton [IDA]
- chylomicron [IDA]
- chylomicron remnant [TAS]
- clathrin-coated endocytic vesicle membrane [TAS]
- cytoplasm [IDA]
- cytosol [TAS]
- early endosome [TAS]
- endocytic vesicle lumen [TAS]
- endoplasmic reticulum lumen [TAS]
- endoplasmic reticulum membrane [TAS]
- endosome lumen [TAS]
- endosome membrane [TAS]
- extracellular region [TAS]
- extracellular space [ISS]
- extracellular vesicular exosome [IDA]
- intermediate-density lipoprotein particle [IDA]
- intracellular membrane-bounded organelle [TAS]
- low-density lipoprotein particle [IDA]
- mature chylomicron [IDA]
- plasma membrane [IDA, TAS]
- very-low-density lipoprotein particle [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Effect of the NF?B-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.
Connexin 43- (Cx43-) mediated nuclear factor kappa-light-chain-enhancer of activated B cell (NF-?B) signaling has been found involved in the ossification of the posterior longitudinal ligament (OPLL). However, the underlying mechanism how OPLL is regulated has not been elucidated. In the present study, primary ligament fibroblast were isolated; immunoprecipitation (IP) and liquid chromatography-mass spectrometry (LC-MS) assays were applied to identify potential ... [more]
Oxid Med Cell Longev Apr. 09, 2022; 2022();1604932 [Pubmed: 35391932]
Throughput
- Low Throughput
Curated By
- BioGRID