BAIT

TMEM173

2610307O08Rik, ERIS, MPYS, Mita, STING
transmembrane protein 173
Mus musculus
PREY

TES

D6Ertd352e, TESS, Tes1, Tes2, testin2
testis derived transcript
GO Process (1)
GO Function (2)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING).

Motani K, Kosako H

Stimulator of interferon genes (STING) mediates cytosolic DNA-induced innate immune signaling via membrane trafficking. The global identification of proteins that spatiotemporally interact with STING will provide a better understanding of its trafficking mechanisms and of STING signaling pathways. Proximity-dependent biotin identification (BioID) is a powerful technology to identify physiologically relevant protein-protein interactions in living cells. However, biotinylated peptides are rarely ... [more]

J Biol Chem Dec. 07, 2019; 295(32);11174-11183 [Pubmed: 32554809]

Throughput

  • High Throughput

Additional Notes

  • TurboID fused-STING, peptides were filtered at a false discovery rate (FDR) of 1%.

Curated By

  • BioGRID