Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence.

He X, Yang Z, Chu XY, Li YX, Zhu B, Huang YX, Wang W, Gao CY, Chen X, Zheng CY, Yang K, Zhang DL

Cellular senescence severely limits the research and the application of dental pulp stem cells (DPSCs). A previous study conducted by our research group revealed a close implication of ROR2 in DPSC senescence, although the mechanism underlying the regulation of ROR2 in DPSCs remains poorly understood so far. In the present study, it was revealed that the expression of the ROR2-interacting ... [more]

Stem Cells Dec. 31, 2021; 40(3);290-302 [Pubmed: 35356984]

Throughput

  • High Throughput

Curated By

  • BioGRID