BAIT
ATG5
2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337, Paddy
autophagy related 5
GO Process (23)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- C-terminal protein lipidation [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- blood vessel remodeling [IMP]
- cellular response to nitrogen starvation [IBA]
- heart contraction [IMP]
- mitochondrion degradation [IBA]
- negative regulation of apoptotic process [IMP]
- negative regulation of histone H4-K16 acetylation [IMP]
- negative regulation of protein ubiquitination [IMP]
- negative stranded viral RNA replication [IMP]
- nucleophagy [IBA]
- otolith development [IMP]
- positive regulation of mucus secretion [IMP]
- post-translational protein modification [IDA]
- regulation of cilium assembly [IMP]
- regulation of cytokine secretion involved in immune response [IMP]
- regulation of reactive oxygen species metabolic process [IMP]
- regulation of release of sequestered calcium ion into cytosol [IMP]
- response to drug [IMP]
- response to fungus [IMP]
- vasodilation [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB13
0610007N03Rik, B230212B15Rik
RAB13, member RAS oncogene family
GO Process (15)
GO Function (4)
GO Component (19)
Gene Ontology Biological Process
- GTP catabolic process [ISO]
- Rab protein signal transduction [IBA]
- cellular response to insulin stimulus [ISO]
- cortical actin cytoskeleton organization [IBA, ISO]
- endocytic recycling [IMP, ISO]
- endosomal transport [ISO]
- endothelial cell chemotaxis [IMP]
- establishment of Sertoli cell barrier [ISO]
- establishment of protein localization to plasma membrane [ISO]
- intracellular protein transport [TAS]
- neuron projection development [ISO]
- protein kinase A signaling [ISO]
- protein localization to cell leading edge [IMP]
- protein localization to plasma membrane [ISO]
- tight junction assembly [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- cell [IMP]
- cell-cell junction [IDA]
- cytoplasm [ISO]
- cytoplasmic membrane-bounded vesicle [TAS]
- cytoplasmic vesicle [ISO]
- endocytic vesicle [IDA, ISO]
- endosome [IBA]
- extracellular vesicular exosome [ISO]
- extrinsic component of plasma membrane [TAS]
- insulin-responsive compartment [ISO]
- intracellular [IMP]
- lamellipodium [IDA]
- lateral plasma membrane [ISO]
- neuron projection [ISO]
- plasma membrane [ISO]
- recycling endosome [ISO]
- tight junction [IDA, ISO]
- trans-Golgi network [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.
Autophagosome formation involves the sequential actions of conserved ATG proteins to coordinate the lipidation of the ubiquitin-like modifier Atg8-family proteins at the nascent phagophore membrane. Although the molecular steps driving this process are well understood, the source of membranes for the expanding phagophore and their mode of delivery are only now beginning to be revealed. Here, we have used quantitative ... [more]
Autophagy Rep Apr. 23, 2022; 1(1);88-118 [Pubmed: 35449600]
Throughput
- Low Throughput
Curated By
- BioGRID