BAIT
ATG5
2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337, Paddy
autophagy related 5
GO Process (23)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- C-terminal protein lipidation [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- blood vessel remodeling [IMP]
- cellular response to nitrogen starvation [IBA]
- heart contraction [IMP]
- mitochondrion degradation [IBA]
- negative regulation of apoptotic process [IMP]
- negative regulation of histone H4-K16 acetylation [IMP]
- negative regulation of protein ubiquitination [IMP]
- negative stranded viral RNA replication [IMP]
- nucleophagy [IBA]
- otolith development [IMP]
- positive regulation of mucus secretion [IMP]
- post-translational protein modification [IDA]
- regulation of cilium assembly [IMP]
- regulation of cytokine secretion involved in immune response [IMP]
- regulation of reactive oxygen species metabolic process [IMP]
- regulation of release of sequestered calcium ion into cytosol [IMP]
- response to drug [IMP]
- response to fungus [IMP]
- vasodilation [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
WNK1
6430573H23Rik, EG406236, Hsn2, Prkwnk1, mKIAA0344
WNK lysine deficient protein kinase 1
GO Process (10)
GO Function (10)
GO Component (1)
Gene Ontology Biological Process
- intracellular signal transduction [ISO]
- ion transport [IDA]
- negative regulation of kinase activity [ISO]
- negative regulation of pancreatic juice secretion [IMP]
- negative regulation of phosphatase activity [ISO]
- negative regulation of protein serine/threonine kinase activity [ISO]
- positive regulation of systemic arterial blood pressure [IMP]
- protein autophosphorylation [ISO]
- protein phosphorylation [IDA, ISO]
- regulation of cellular process [IDA]
Gene Ontology Molecular Function- ATP binding [ISO]
- chloride channel inhibitor activity [ISO]
- magnesium ion binding [ISO]
- phosphatase binding [ISO]
- potassium channel inhibitor activity [ISO]
- protein binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein serine/threonine kinase activity [ISO]
- protein serine/threonine kinase inhibitor activity [ISO]
- ATP binding [ISO]
- chloride channel inhibitor activity [ISO]
- magnesium ion binding [ISO]
- phosphatase binding [ISO]
- potassium channel inhibitor activity [ISO]
- protein binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein serine/threonine kinase activity [ISO]
- protein serine/threonine kinase inhibitor activity [ISO]
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.
Autophagosome formation involves the sequential actions of conserved ATG proteins to coordinate the lipidation of the ubiquitin-like modifier Atg8-family proteins at the nascent phagophore membrane. Although the molecular steps driving this process are well understood, the source of membranes for the expanding phagophore and their mode of delivery are only now beginning to be revealed. Here, we have used quantitative ... [more]
Autophagy Rep Apr. 23, 2022; 1(1);88-118 [Pubmed: 35449600]
Throughput
- Low Throughput
Curated By
- BioGRID