BAIT
ATG5
2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337, Paddy
autophagy related 5
GO Process (23)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- C-terminal protein lipidation [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- blood vessel remodeling [IMP]
- cellular response to nitrogen starvation [IBA]
- heart contraction [IMP]
- mitochondrion degradation [IBA]
- negative regulation of apoptotic process [IMP]
- negative regulation of histone H4-K16 acetylation [IMP]
- negative regulation of protein ubiquitination [IMP]
- negative stranded viral RNA replication [IMP]
- nucleophagy [IBA]
- otolith development [IMP]
- positive regulation of mucus secretion [IMP]
- post-translational protein modification [IDA]
- regulation of cilium assembly [IMP]
- regulation of cytokine secretion involved in immune response [IMP]
- regulation of reactive oxygen species metabolic process [IMP]
- regulation of release of sequestered calcium ion into cytosol [IMP]
- response to drug [IMP]
- response to fungus [IMP]
- vasodilation [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ECT2
AI528536, mKIAA4037
ect2 oncogene
GO Process (20)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- activation of Rac GTPase activity [ISO]
- activation of Rho GTPase activity [ISO]
- activation of protein kinase activity [ISO]
- cell morphogenesis [IDA]
- cellular response to calcium ion [ISO]
- cellular response to hydrogen peroxide [ISO]
- cellular response to ionizing radiation [ISO]
- cytokinesis [ISO]
- positive regulation of Cdc42 GTPase activity [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of Rho GTPase activity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron differentiation [IMP]
- positive regulation of protein import into nucleus [IDA]
- protein homooligomerization [ISO]
- regulation of attachment of spindle microtubules to kinetochore [ISO]
- regulation of protein kinase activity [ISO]
- signal transduction [ISO]
- tight junction assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.
Autophagosome formation involves the sequential actions of conserved ATG proteins to coordinate the lipidation of the ubiquitin-like modifier Atg8-family proteins at the nascent phagophore membrane. Although the molecular steps driving this process are well understood, the source of membranes for the expanding phagophore and their mode of delivery are only now beginning to be revealed. Here, we have used quantitative ... [more]
Autophagy Rep Apr. 23, 2022; 1(1);88-118 [Pubmed: 35449600]
Throughput
- Low Throughput
Curated By
- BioGRID