BAIT
ATG5
2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337, Paddy
autophagy related 5
GO Process (23)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- C-terminal protein lipidation [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- blood vessel remodeling [IMP]
- cellular response to nitrogen starvation [IBA]
- heart contraction [IMP]
- mitochondrion degradation [IBA]
- negative regulation of apoptotic process [IMP]
- negative regulation of histone H4-K16 acetylation [IMP]
- negative regulation of protein ubiquitination [IMP]
- negative stranded viral RNA replication [IMP]
- nucleophagy [IBA]
- otolith development [IMP]
- positive regulation of mucus secretion [IMP]
- post-translational protein modification [IDA]
- regulation of cilium assembly [IMP]
- regulation of cytokine secretion involved in immune response [IMP]
- regulation of reactive oxygen species metabolic process [IMP]
- regulation of release of sequestered calcium ion into cytosol [IMP]
- response to drug [IMP]
- response to fungus [IMP]
- vasodilation [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FERT2
AV082135, C330004K01Rik, Fer, Fert
fer (fms/fps related) protein kinase, testis specific 2
GO Process (39)
GO Function (14)
GO Component (8)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [IMP]
- Kit signaling pathway [IMP]
- actin cytoskeleton reorganization [IMP]
- cell adhesion [IMP]
- cell proliferation [ISO]
- cell-cell adhesion mediated by cadherin [IMP]
- cellular response to insulin stimulus [IDA]
- cellular response to macrophage colony-stimulating factor stimulus [ISO]
- cellular response to reactive oxygen species [IMP]
- chemotaxis [IMP]
- cytokine-mediated signaling pathway [ISO]
- diapedesis [IMP]
- epidermal growth factor receptor signaling pathway [IBA]
- extracellular matrix-cell signaling [IMP]
- innate immune response [IBA]
- insulin receptor signaling pathway via phosphatidylinositol 3-kinase [IDA]
- interleukin-6-mediated signaling pathway [ISO]
- microtubule cytoskeleton organization [ISO]
- mitotic cell cycle [ISO]
- negative regulation of mast cell activation involved in immune response [IMP]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO]
- platelet-derived growth factor receptor signaling pathway [IDA]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of cell migration [ISO]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [IDA]
- regulation of cell proliferation [IBA]
- regulation of epidermal growth factor receptor signaling pathway [ISO]
- regulation of fibroblast migration [IMP]
- regulation of lamellipodium assembly [ISO]
- regulation of mast cell degranulation [IBA]
- regulation of protein phosphorylation [IMP]
- response to lipopolysaccharide [IMP]
- response to platelet-derived growth factor [IDA]
- signal transduction [IDA]
- substrate adhesion-dependent cell spreading [IMP]
- tyrosine phosphorylation of Stat3 protein [ISO]
Gene Ontology Molecular Function- Rab GTPase binding [ISO]
- actin binding [ISO]
- cadherin binding [ISO]
- cell adhesion molecule binding [ISO]
- cytoskeletal protein binding [ISO]
- epidermal growth factor receptor binding [ISO]
- gamma-catenin binding [ISO]
- lipid binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO]
- protein binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein phosphatase 1 binding [IPI]
- receptor binding [IBA]
- Rab GTPase binding [ISO]
- actin binding [ISO]
- cadherin binding [ISO]
- cell adhesion molecule binding [ISO]
- cytoskeletal protein binding [ISO]
- epidermal growth factor receptor binding [ISO]
- gamma-catenin binding [ISO]
- lipid binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO]
- protein binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein phosphatase 1 binding [IPI]
- receptor binding [IBA]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.
Autophagosome formation involves the sequential actions of conserved ATG proteins to coordinate the lipidation of the ubiquitin-like modifier Atg8-family proteins at the nascent phagophore membrane. Although the molecular steps driving this process are well understood, the source of membranes for the expanding phagophore and their mode of delivery are only now beginning to be revealed. Here, we have used quantitative ... [more]
Autophagy Rep Apr. 23, 2022; 1(1);88-118 [Pubmed: 35449600]
Throughput
- Low Throughput
Curated By
- BioGRID