BAIT
ARL4C
ARL7, LAK
ADP-ribosylation factor-like 4C
GO Process (2)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SLC30A1
ZNT1, ZRC1
solute carrier family 30 (zinc transporter), member 1
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- cadmium ion transmembrane transport [ISS]
- cellular calcium ion homeostasis [ISS]
- cellular zinc ion homeostasis [ISS]
- negative regulation of calcium ion import [ISS]
- negative regulation of neurotransmitter secretion [ISS]
- negative regulation of zinc ion transmembrane import [ISS]
- transmembrane transport [TAS]
- zinc ion transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.
The Arf GTPase family is involved in a wide range of cellular regulation including membrane trafficking and organelle-structure assembly. Here, we have generated a proximity interaction network for the Arf family using the miniTurboID approach combined with TMT-based quantitative mass spectrometry. Our interactome confirmed known interactions and identified many novel interactors that provide leads for defining Arf pathway cell biological ... [more]
EMBO J Jul. 17, 2022; ();e110698 [Pubmed: 35844135]
Throughput
- High Throughput
Additional Notes
- Constitutively active mutant of GTPase fused with miniTurboID was stably expressed in HEK293A cells, followed by miniTurboID experiment and TMT-based mass spectrometry. FDR threshold of 0.05
Curated By
- BioGRID