BAIT

HDAC6

CPBHM, HD6, PPP1R90, JM21
histone deacetylase 6
GO Process (31)
GO Function (14)
GO Component (16)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

Xu X, Ding P, Shi L, Wu G, Ma X

Hepatocellular carcinoma (HCC) is a clinically common malignant tumor worldwide. LukS-PV is the S component of Panton-Valentine leukocidin secreted by Staphylococcus aureus, which has shown anti-cancer activity. Based on previous findings, this study investigated the effects of LukS-PV on HCC migration and the potential molecular mechanisms involving acetylation pathways.After treating HCC cells with different concentrations of LukS-PV, we used scratch ... [more]

BMC Cancer Jun. 08, 2022; 22(1);630 [Pubmed: 35676659]

Throughput

  • Low Throughput

Curated By

  • BioGRID