MYO1C
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- innate immune response [TAS]
- membrane organization [TAS]
- positive regulation of cell migration [IMP]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [IMP]
- positive regulation of protein targeting to membrane [IMP]
- positive regulation of vascular endothelial growth factor signaling pathway [IMP]
- protein targeting [IDA]
- protein targeting to membrane [IDA]
- regulation of tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- filamentous actin [IDA]
- lateral plasma membrane [IDA]
- membrane [IDA]
- membrane raft [IDA]
- microvillus [IDA]
- mitochondrion [IDA]
- nucleoplasm [IDA]
- plasma membrane [IDA]
- stress fiber [IDA]
- unconventional myosin complex [TAS]
BAZ1B
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- chromatin-mediated maintenance of transcription [ISS]
- double-strand break repair [ISS]
- heart morphogenesis [ISS]
- histone phosphorylation [IDA]
- peptidyl-tyrosine phosphorylation [IDA]
- regulation of transcription, DNA-templated [ISS]
- transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.646)
- MCF7 cell line (score 0.689)
- MDA231 cell line (score 0.653)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
BAZ1B MYO1C | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
BAZ1B MYO1C | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
MYO1C BAZ1B | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID