BAIT
KIF1B
CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1, RP4-736L20.1
kinesin family member 1B
GO Process (6)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HMGB2
HMG2
high mobility group box 2
GO Process (22)
GO Function (12)
GO Component (7)
Gene Ontology Biological Process
- DNA ligation involved in DNA repair [ISS]
- DNA topological change [ISS]
- V(D)J recombination [ISS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- base-excision repair, DNA ligation [IDA]
- cell chemotaxis [IDA]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cellular response to lipopolysaccharide [IEP]
- chromatin organization [NAS]
- chromatin remodeling [IBA]
- negative regulation of transcription, DNA-templated [IDA]
- nucleosome assembly [NAS]
- positive chemotaxis [IDA]
- positive regulation of DNA binding [IDA]
- positive regulation of endothelial cell proliferation [IDA]
- positive regulation of erythrocyte differentiation [IMP]
- positive regulation of megakaryocyte differentiation [IMP]
- positive regulation of nuclease activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IMP]
- DNA binding, bending [IDA]
- RAGE receptor binding [IGI]
- chemoattractant activity [IDA]
- chromatin binding [IBA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IMP]
- DNA binding, bending [IDA]
- RAGE receptor binding [IGI]
- chemoattractant activity [IDA]
- chromatin binding [IBA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.709)
Curated By
- BioGRID