BAIT
FARP2
FIR, FRG, PLEKHC3
FERM, RhoGEF and pleckstrin domain protein 2
GO Process (11)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- Rac protein signal transduction [IDA]
- actin cytoskeleton reorganization [ISS]
- axon guidance [TAS]
- cell adhesion [ISS]
- neuron remodeling [IDA]
- osteoclast differentiation [ISS]
- podosome assembly [ISS]
- positive regulation of Rac GTPase activity [ISS]
- positive regulation of Rho GTPase activity [IDA]
- regulation of integrin activation [ISS]
- semaphorin-plexin signaling pathway [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
BSG
5F7, CD147, EMMPRIN, M6, OK, TCSF, UNQ6505/PRO21383
basigin (Ok blood group)
GO Process (9)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular metabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- leukocyte migration [TAS]
- protein targeting to plasma membrane [ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF7 cell line (score 0.642)
Curated By
- BioGRID