BAIT
PARN
DAN
poly(A)-specific ribonuclease
GO Process (10)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA modification [TAS]
- RNA phosphodiester bond hydrolysis, exonucleolytic [TAS]
- female gamete generation [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- nucleic acid phosphodiester bond hydrolysis [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
GLMN
FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM
glomulin, FKBP associated protein
GO Process (9)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- muscle cell differentiation [IMP]
- negative regulation of T cell proliferation [IDA]
- negative regulation of protein ubiquitination [IGI]
- positive regulation of cytokine secretion [IMP]
- positive regulation of interleukin-2 biosynthetic process [IMP]
- positive regulation of phosphorylation [IDA]
- regulation of gene expression, epigenetic [IMP]
- regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- vasculogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF7 cell line (score 0.685)
Curated By
- BioGRID