BAIT
PNP
NP, PRO1837, PUNP
purine nucleoside phosphorylase
GO Process (15)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- NAD biosynthesis via nicotinamide riboside salvage pathway [IGI]
- immune response [IMP]
- inosine catabolic process [IDA]
- interleukin-2 secretion [IMP]
- nicotinamide riboside catabolic process [IDA]
- nucleobase-containing compound metabolic process [IDA]
- nucleobase-containing small molecule metabolic process [TAS]
- positive regulation of T cell proliferation [IDA]
- positive regulation of alpha-beta T cell differentiation [IDA]
- purine nucleobase metabolic process [TAS]
- purine nucleotide catabolic process [TAS]
- purine-containing compound salvage [TAS]
- response to drug [IDA, IMP]
- small molecule metabolic process [TAS]
- urate biosynthetic process [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VAPA
VAP-33, VAP-A, VAP33, hVAP-33
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
GO Process (16)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- COPII-coated vesicle budding [IMP]
- ER to Golgi vesicle-mediated transport [IMP]
- cell death [IMP]
- endoplasmic reticulum organization [IMP]
- membrane fusion [TAS]
- negative regulation by host of viral genome replication [IDA]
- neuron projection development [IMP]
- positive regulation by host of viral genome replication [IDA]
- positive regulation by host of viral release from host cell [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- protein folding in endoplasmic reticulum [IMP]
- protein localization to endoplasmic reticulum [IMP]
- signal transduction [IMP]
- small molecule metabolic process [TAS]
- sphingolipid biosynthetic process [TAS]
- sphingolipid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.637)
Curated By
- BioGRID