SOD2
Gene Ontology Biological Process
- age-dependent response to reactive oxygen species [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of neuron apoptotic process [IGI]
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [IMP]
- oxygen homeostasis [IMP]
- protein homotetramerization [IPI]
- regulation of blood pressure [ISS]
- regulation of transcription from RNA polymerase II promoter [IMP]
- release of cytochrome c from mitochondria [ISS]
- removal of superoxide radicals [IMP]
- response to superoxide [IMP]
- superoxide metabolic process [IDA]
- vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ABAT
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.655)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SOD2 ABAT | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.1166 | BioGRID | 1257963 |
Curated By
- BioGRID