BAIT
UNG
DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2
uracil-DNA glycosylase
GO Process (1)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PPID
CYP-40, CYPD
peptidylprolyl isomerase D
GO Process (10)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- cellular response to UV-A [IMP]
- chaperone-mediated protein folding [IDA]
- lipid particle organization [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of protein secretion [IMP]
- positive regulation of viral genome replication [IMP]
- protein complex assembly [IDA]
- protein folding [ISS]
- viral release from host cell [TAS]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.654)
Curated By
- BioGRID