BAIT
LGALS3
CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
lectin, galactoside-binding, soluble, 3
GO Process (18)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- eosinophil chemotaxis [IDA]
- epithelial cell differentiation [IEP]
- innate immune response [TAS]
- macrophage chemotaxis [IDA]
- monocyte chemotaxis [IDA]
- mononuclear cell migration [IDA]
- negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [ISS]
- negative regulation of T cell receptor signaling pathway [ISS]
- negative regulation of endocytosis [IDA]
- negative regulation of extrinsic apoptotic signaling pathway [IDA]
- negative regulation of immunological synapse formation [ISS]
- neutrophil chemotaxis [IDA]
- positive chemotaxis [IDA]
- positive regulation of calcium ion import [IDA]
- positive regulation of mononuclear cell migration [IDA]
- regulation of T cell apoptotic process [IDA]
- regulation of T cell proliferation [IMP]
- regulation of extrinsic apoptotic signaling pathway via death domain receptors [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SNRPD1
HsT2456, SMD1, SNRPD, Sm-D1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
GO Process (7)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.711)
- MCF7 cell line (score 0.684)
- MDA231 cell line (score 0.704)
Curated By
- BioGRID