BAIT
SCP2
NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX
sterol carrier protein 2
GO Process (15)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- inositol trisphosphate biosynthetic process [IDA]
- lipid hydroperoxide transport [IDA]
- phospholipid transport [IDA]
- positive regulation of intracellular cholesterol transport [IDA, NAS]
- positive regulation of steroid metabolic process [IDA]
- progesterone biosynthetic process [IDA]
- protein localization to plasma membrane [IDA]
- small molecule metabolic process [TAS]
- steroid biosynthetic process [IDA]
- unsaturated fatty acid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SFPQ
POMP100, PPP1R140, PSF
splicing factor proline/glutamine-rich
GO Process (9)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- RNA splicing [TAS]
- alternative mRNA splicing, via spliceosome [IMP]
- histone H3 deacetylation [ISS]
- mRNA processing [TAS]
- negative regulation of circadian rhythm [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [IDA]
- regulation of circadian rhythm [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.657)
Curated By
- BioGRID