BAIT
S100A4
18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98
S100 calcium binding protein A4
GO Process (2)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GPD1L
GPD1-L
glycerol-3-phosphate dehydrogenase 1-like
GO Process (15)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- NAD metabolic process [IMP]
- cellular lipid metabolic process [TAS]
- glycerophospholipid biosynthetic process [TAS]
- negative regulation of peptidyl-serine phosphorylation [IMP]
- negative regulation of protein kinase C signaling [IMP]
- phosphatidic acid biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- positive regulation of protein localization to cell surface [IMP]
- positive regulation of sodium ion transport [IMP]
- regulation of heart rate [IMP]
- regulation of sodium ion transmembrane transporter activity [IMP]
- regulation of ventricular cardiac muscle cell membrane depolarization [IMP]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
- ventricular cardiac muscle cell action potential [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.651)
Curated By
- BioGRID