BAIT
COPROX
BcDNA:GM14838, CG3433, Dmel\CG3433, l(2)k10617, l(2)k11018, Dmel_CG3433
Coproporphyrinogen oxidase
GO Process (1)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
DL
CG6667, Dmel\CG6667, Dor, Dorsal, GSd447, NFkappaB, REL, anon-EST:GressD7, d, fs(2)k10816, mat(2)dorsal, Dmel_CG6667
dorsal
GO Process (28)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- Toll signaling pathway [NAS, TAS]
- anterior/posterior pattern specification [TAS]
- defense response [NAS, TAS]
- dorsal/ventral axis specification [TAS]
- dorsal/ventral pattern formation [NAS]
- ectoderm development [NAS]
- ectodermal cell fate specification [TAS]
- gastrulation [NAS]
- gastrulation involving germ band extension [TAS]
- germ cell migration [TAS]
- heart development [NAS]
- immune response [IEP, NAS, TAS]
- maternal determination of anterior/posterior axis, embryo [IMP]
- melanization defense response [IMP]
- mesoderm development [NAS]
- mesodermal cell fate specification [TAS]
- negative regulation of gene expression [IDA]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [NAS, TAS]
- peripheral nervous system neuron development [IMP]
- plasmatocyte differentiation [IMP]
- positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- positive regulation of transcription, DNA-templated [IDA, TAS]
- regulation of alternative mRNA splicing, via spliceosome [IMP]
- regulation of hemocyte proliferation [IDA]
- regulation of transcription, DNA-templated [ISS, NAS]
- ventral cord development [NAS]
Gene Ontology Molecular Function- DNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IGI]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- high mobility group box 1 binding [IPI]
- morphogen activity [NAS]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
- DNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IGI]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- high mobility group box 1 binding [IPI]
- morphogen activity [NAS]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID