BAIT
RBMX
HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G, RP11-1114A5.1
RNA binding motif protein, X-linked
GO Process (12)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- RNA splicing [TAS]
- cellular response to interleukin-1 [IDA]
- gene expression [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- membrane protein ectodomain proteolysis [IDA]
- negative regulation of mRNA splicing, via spliceosome [ISS]
- osteoblast differentiation [IDA]
- positive regulation of mRNA splicing, via spliceosome [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein homooligomerization [ISS]
- regulation of alternative mRNA splicing, via spliceosome [IDA]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
USP7
HAUSP, TEF1
ubiquitin specific peptidase 7 (herpes virus-associated)
GO Process (8)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- histone deubiquitination [IBA]
- maintenance of DNA methylation [IMP]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IDA, IMP]
- regulation of proteasomal protein catabolic process [IBA]
- regulation of sequence-specific DNA binding transcription factor activity [IDA]
- transcription-coupled nucleotide-excision repair [IMP]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.751)
- MDA231 cell line (score 0.763)
Curated By
- BioGRID