RAB10
Gene Ontology Biological Process
- GTP catabolic process [IBA]
- Golgi to plasma membrane protein transport [ISS]
- Golgi to plasma membrane transport [ISS]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [IMP]
- axonogenesis [ISS]
- basolateral protein localization [ISS]
- cellular response to insulin stimulus [IBA, ISS]
- endoplasmic reticulum tubular network organization [IMP]
- endosomal transport [IMP]
- establishment of neuroblast polarity [ISS]
- establishment of protein localization to endoplasmic reticulum membrane [IMP]
- establishment of protein localization to membrane [IMP]
- intracellular protein transport [IBA]
- membrane organization [TAS]
- polarized epithelial cell differentiation [ISS]
- protein localization to plasma membrane [IBA, ISS]
- protein secretion [IBA]
- regulation of exocytosis [IBA]
- vesicle docking involved in exocytosis [IBA]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- cytoplasmic vesicle membrane [TAS]
- endoplasmic reticulum membrane [IDA]
- endoplasmic reticulum tubular network [IDA]
- endosome [IDA]
- endosome membrane [IBA]
- exocyst [ISS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- insulin-responsive compartment [IDA]
- plasma membrane [IDA]
- primary cilium [IDA]
- recycling endosome [IDA]
- trans-Golgi network [ISS]
RAB1B
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.644)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RAB10 RAB1B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3365529 |
Curated By
- BioGRID