BAIT
PFKP
ATP-PFK, PFK-C, PFK-P, PFKF, RP11-298E9.2
phosphofructokinase, platelet
GO Process (5)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
GO Process (8)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- DNA ligation involved in DNA repair [IDA]
- DNA repair [TAS]
- double-strand break repair [IDA, TAS]
- double-strand break repair via nonhomologous end joining [IDA, IMP, NAS, TAS]
- establishment of integrated proviral latency [TAS]
- positive regulation of ligase activity [IDA]
- response to X-ray [IDA]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.753)
Curated By
- BioGRID