ESG
Gene Ontology Biological Process
- asymmetric neuroblast division [IGI]
- branch fusion, open tracheal system [IMP, TAS]
- cell fate determination [IMP]
- cell fate specification [IMP]
- central nervous system development [IGI, IMP]
- epithelial cell migration, open tracheal system [IMP]
- fusion cell fate specification [TAS]
- genital disc development [IMP]
- germ-line stem cell maintenance [IMP]
- gravitaxis [IMP]
- maintenance of imaginal histoblast diploidy [IMP]
- negative regulation of DNA endoreduplication [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- olfactory behavior [IMP]
- open tracheal system development [IMP, NAS, TAS]
- peripheral nervous system development [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of compound eye pigmentation [IMP]
- regulation of transcription from RNA polymerase II promoter [ISS]
- wing disc development [IMP]
Gene Ontology Molecular Function
CTBP
Gene Ontology Biological Process
- Wnt signaling pathway [IGI]
- chaeta development [IMP]
- embryonic development via the syncytial blastoderm [IMP]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of JAK-STAT cascade [IMP]
- regulation of Wnt signaling pathway [IMP]
- regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of transcription, DNA-templated [IMP]
- sensory organ precursor cell fate determination [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
ESG CTBP | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - |
Curated By
- BioGRID