BAIT
PPP1R9B
PPP1R6, PPP1R9, SPINO, Spn
protein phosphatase 1, regulatory subunit 9B
GO Process (11)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- RNA splicing [NAS]
- cell cycle arrest [TAS]
- cell migration [IMP]
- cellular response to morphine [ISS]
- filopodium assembly [IMP]
- negative regulation of catalytic activity [NAS]
- negative regulation of cell growth [IDA]
- regulation of cell growth by extracellular stimulus [TAS]
- regulation of cell proliferation [NAS]
- regulation of exit from mitosis [NAS]
- regulation of opioid receptor signaling pathway [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
COPS4
CSN4
COP9 signalosome subunit 4
GO Process (2)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.631)
Curated By
- BioGRID