BAIT
TBCD
SSD-1, tfcD, PP1096
tubulin folding cofactor D
GO Process (9)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- 'de novo' posttranslational protein folding [TAS]
- adherens junction assembly [IBA, ISS]
- cellular protein metabolic process [TAS]
- negative regulation of cell-substrate adhesion [ISS]
- negative regulation of microtubule polymerization [IDA]
- positive regulation of GTPase activity [IDA, IMP]
- post-chaperonin tubulin folding pathway [IDA]
- protein folding [IDA, TAS]
- tight junction assembly [IBA, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KLC2
kinesin light chain 2
GO Process (3)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.642)
Curated By
- BioGRID