BAIT
PDLIM7
LMP1, LMP3
PDZ and LIM domain 7 (enigma)
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ERAP1
A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP, UNQ584/PRO1154
endoplasmic reticulum aminopeptidase 1
GO Process (8)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- angiogenesis [TAS]
- antigen processing and presentation of endogenous peptide antigen via MHC class I [NAS, TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- fat cell differentiation [NAS]
- membrane protein ectodomain proteolysis [IDA]
- regulation of blood pressure [NAS, TAS]
- regulation of innate immune response [NAS]
- response to bacterium [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.64)
Curated By
- BioGRID