BAIT
RNF125
TRAC-1, TRAC1
ring finger protein 125, E3 ubiquitin protein ligase
GO Process (2)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
PREY
CTTN
EMS1
cortactin
GO Process (9)
GO Function (1)
GO Component (12)
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISS]
- cell motility [ISS]
- focal adhesion assembly [ISS]
- intracellular protein transport [IMP]
- lamellipodium organization [ISS]
- neuron projection morphogenesis [ISS]
- positive regulation of actin filament polymerization [ISS]
- receptor-mediated endocytosis [ISS]
- regulation of axon extension [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Down-regulation of circPTTG1IP induces hepatocellular carcinoma development via miR-16-5p/RNF125/JAK1 axis.
Circular RNAs are known to regulate the biological processes of hepatocellular carcinoma (HCC), and humans with Down syndrome are at low risk of developing solid tumors due to the amplification of several tumor suppressor genes on human chromosome 21 (HSA21). Here, we aimed to investigate the potential role of circRNAs originating from HSA21 in the progression of HCC. CircRNA-sequencing was ... [more]
Cancer Lett Dec. 01, 2021; 543();215778 [Pubmed: 35710093]
Throughput
- Low Throughput
Curated By
- BioGRID