BAIT

PPP2R2A

pp2a
protein phosphatase 2, regulatory subunit B, alpha
GO Process (0)
GO Function (0)
GO Component (0)
Xenopus laevis
PREY

AURKB-A

AIRK2-A, AurB, XAIRK2-A, aik2, aim1, ark2, aurkb, ipl1, stk12, stk5
aurora kinase B
GO Process (0)
GO Function (0)
GO Component (0)
Xenopus laevis

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress.

Wang F, Zhu S, Fisher LA, Wang W, Oakley GG, Li C, Peng A

The specific function of PP2A, a major serine/threonine phosphatase, is mediated by regulatory targeting subunits, such as members of the B55 family. Although implicated in cell division and other pathways, the specific substrates and functions of B55 targeting subunits are largely undefined. In this study we identified over 100 binding proteins of B55? and B55? in Xenopus egg extracts that ... [more]

Sci Rep Dec. 08, 2017; 8(1);2683 [Pubmed: 29422626]

Throughput

  • High Throughput

Curated By

  • BioGRID