BAIT

USP53

ubiquitin specific peptidase 53
UPS Project
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

TMOD2

N-TMOD, NTMOD
tropomodulin 2 (neuronal)
GO Process (4)
GO Function (0)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

Yao Y, Ma W, Guo Y, Liu Y, Xia P, Wu X, Chen Y, Wang K, Mei C, Wang G, Li X, Zhang Z, Chen X, Yuan Y

Despite of advances in treatment options, hepatocellular carcinoma (HCC) remains nearly incurable and has been recognized as the third leading cause of cancer-related deaths worldwide. As a deubiquitinating enzyme, the antitumor effect of ubiquitin-specific peptidase 53 (USP53) has been demonstrated on few malignancies. In this study, we investigated the potential antitumor role of USP53 in HCC. The results showed that ... [more]

Oncogenesis Jun. 02, 2022; 11(1);31 [Pubmed: 35654790]

Throughput

  • Low Throughput

Curated By

  • BioGRID