BAIT

ZXDA

ZNF896
zinc finger, X-linked, duplicated A
GO Process (1)
GO Function (3)
GO Component (0)
Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.

Dibus N, Korinek V, Cermak L

Alterations in the gene encoding the E3 ubiquitin ligase substrate receptor FBXO38 have been associated with several diseases, including early-onset motor neuronopathy. However, the cellular processes affected by the enzymatic action of FBXO38 are not yet known. Here, we identify the zinc finger proteins ZXDA/B as its interaction partners. FBXO38 controls the stability of ZXDA/B proteins via ubiquitination and proteasome-dependent ... [more]

Front Cell Dev Biol Jul. 12, 2022; 10();929288 [Pubmed: 35813202]

Throughput

  • Low Throughput

Curated By

  • BioGRID