BAIT
EIF4G3
eIF-4G 3, eIF4G 3, eIF4GII, RP11-190H11.1
eukaryotic translation initiation factor 4 gamma, 3
GO Process (2)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TRIM25
EFP, RNF147, Z147, ZNF147
tripartite motif containing 25
GO Process (7)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- innate immune response [IDA, TAS]
- negative regulation of type I interferon production [TAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [IMP]
- regulation of viral entry into host cell [IDA]
- regulation of viral release from host cell [IMP]
Gene Ontology Molecular Function
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of ?-catenin by promoting ?-catenin ubiquitin degradation and upregulating SIK1.
Increasing studies suggest that circular RNAs (circRNAs) are critical regulators of cancer development and progression. However, the biological roles and mechanisms of circRNAs in gastric cancer (GC) remain largely unknown.We identified the differentially expressed circRNAs in GC by analyzing Gene Expression Omnibus (GEO) datasets. We explored the biological roles of circRNAs in GC by in vitro functional assays and in ... [more]
Mol Cancer Dec. 02, 2021; 21(1);141 [Pubmed: 35780119]
Throughput
- Low Throughput
Curated By
- BioGRID