PREY

RGS17

RGS-17, RGSZ2, hRGS17
regulator of G-protein signaling 17
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.

Ajit SK, Ramineni S, Edris W, Hunt RA, Hum WT, Hepler JR, Young KH

Protein kinase C interacting protein (PKCI-1) was identified among the potential interactors from a yeast two hybrid screen of human brain library using N terminal of RGSZ1 as a bait. The cysteine string region, unique to the RZ subfamily, contributes to the observed interaction because PKCI-1 interacted with N-terminus of RGS17 and GAIP, but not with that of RGS2 or ... [more]

Cell. Signal. Apr. 01, 2007; 19(4);723-30 [Pubmed: 17126529]

Throughput

  • Low Throughput

Curated By

  • BioGRID