BAIT

S

spike, SARS-CoV2 S, SARS-CoV2 spike, S protein, surface, SARS-CoV-2 spike, SARS-CoV-2 S, SPIKE_SARS2, PRO_0000449646, GU280_gp02
Spike glycoprotein; Surface glycoprotein
COVID-19 Coronavirus Project
Synthetic Protein Interaction Project
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus 2
PREY

IGF2BP1

CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1
insulin-like growth factor 2 mRNA binding protein 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition.

Iacobucci I, Monaco V, Cane L, Bibbo F, Cioffi V, Cozzolino F, Guarino A, Zollo M, Monti M

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19), which, since 2019 in China, has rapidly become a worldwide pandemic. The aggressiveness and global spread were enhanced by the many SARS-CoV-2 variants that have been isolated up to now. These mutations affect mostly the viral glycoprotein Spike (S), the capsid protein mainly involved in the early stages ... [more]

Front Mol Biosci Oct. 14, 2022; 9();975570 [Pubmed: 36225252]

Throughput

  • High Throughput

Additional Notes

  • Caco-2 colorectal adenocarcinoma cell line
  • High confidence interaction with S1 subunit from SARS-CoV-2 Spike.

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
S IGF2BP1
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
3743726
S IGF2BP1
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

High-BioGRID
3558760
S IGF2BP1
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

High-BioGRID
3777090

Curated By

  • BioGRID