BAIT
SPAG6
PF16
sperm associated antigen 6
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BAZ1B
C87820, WSTF, Wbscr9
bromodomain adjacent to zinc finger domain, 1B
GO Process (10)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [ISO]
- chromatin assembly or disassembly [IDA]
- chromatin remodeling [IDA]
- chromatin-mediated maintenance of transcription [IMP]
- double-strand break repair [IMP]
- heart morphogenesis [IMP]
- histone phosphorylation [ISO]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of receptor activity [IMP]
- regulation of transcription, DNA-templated [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The sperm-associated antigen 6 interactome and its role in spermatogenesis.
Mammalian SPAG6, the orthologue of Chlamydomonas reinhardtii PF16, is a component of the central apparatus of the '9 + 2' axoneme that controls ciliary/flagellar motility, including sperm motility. Recent studies revealed that SPAG6 has functions beyond its role in the central apparatus. Hence, we reexamined the role of SPAG6 in male fertility. In wild-type mice, SPAG6 was present in cytoplasmic ... [more]
Reproduction Dec. 01, 2018; 158(2);181-197 [Pubmed: 31146259]
Throughput
- High Throughput
Curated By
- BioGRID