BAIT
ZRANB1
TRABID, RP11-298J20.4
zinc finger, RAN-binding domain containing 1
GO Process (8)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- cell migration [IMP]
- cytoskeleton organization [IMP]
- positive regulation of Wnt signaling pathway [IMP]
- protein K29-linked deubiquitination [IDA]
- protein K33-linked deubiquitination [IDA]
- protein K63-linked deubiquitination [IDA, IMP]
- protein deubiquitination involved in ubiquitin-dependent protein catabolic process [IMP]
- regulation of cell morphogenesis [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
KIF3B
FLA8, HH0048, KLP-11
kinesin family member 3B
GO Process (13)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- anterograde axon cargo transport [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- cytoskeleton-dependent intracellular transport [IBA]
- determination of left/right symmetry [TAS]
- membrane organization [TAS]
- metabolic process [IBA, TAS]
- microtubule-based movement [IBA, TAS]
- mitotic centrosome separation [TAS]
- mitotic spindle organization [TAS]
- plus-end-directed vesicle transport along microtubule [TAS]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRABID targets DDB2 for deubiquitination to promote proliferation of hepatocellular carcinoma cells.
TRAF-binding domain-containing protein (TRABID), a member of the OTU deubiquitinase family, has an important role in regulating cellular functions via deubiquitinating substrate proteins such as EZH2 and Jmjd2d. However, the mechanism of its role in the proliferation of hepatocellular carcinoma (HCC) cells has not been fully elucidated. Here, we analyzed the interactome of TRABID in HepG2 cells through mass spectrometry-based ... [more]
Biochem Biophys Res Commun Dec. 15, 2021; 625();23-30 [Pubmed: 35944360]
Throughput
- Low Throughput
Curated By
- BioGRID