BAIT
CG5355
Dmel\CG5355, Dmel_CG5355
CG5355 gene product from transcript CG5355-RA
GO Process (0)
GO Function (2)
GO Component (0)
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
ARK
APAF-1, APAF1, CG6829, D-Apaf-1, DARK, Dapaf-1, Dapaf-1/HAC-1, Dark/Apaf-I, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, Dark/Hac-1/dApaf1, Dmel\CG6829, Hac-1, Hac-1/Dark, Hac1, T1, anon-53Fa, arc, dApaf-1/DARK/HAC-1, dApaf1, dapaf, dapaf-1L, dapaf-1S, dark/dapaf-1/hac-1, l(2)SH0173, Dmel_CG6829
Apaf-1-related-killer
GO Process (25)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- S-adenosylmethionine cycle [IMP]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IPI, ISS, TAS]
- activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [IMP, TAS]
- apoptotic process [NAS, TAS]
- central nervous system formation [IMP]
- dendrite morphogenesis [IMP]
- histolysis [IMP]
- melanization defense response [IMP]
- negative regulation of humoral immune response [IMP]
- neuron cellular homeostasis [IGI]
- positive regulation of apoptotic process [IGI]
- positive regulation of compound eye retinal cell programmed cell death [IMP]
- positive regulation of glial cell apoptotic process [IMP]
- programmed cell death [IDA, NAS]
- protein heterooligomerization [IDA]
- protein homooligomerization [IDA]
- regulation of retinal cell programmed cell death [NAS]
- response to gamma radiation [IDA]
- response to starvation [IMP]
- salivary gland cell autophagic cell death [IMP]
- salivary gland histolysis [IMP]
- sarcosine catabolic process [IMP]
- sensory organ development [IMP]
- sperm individualization [IMP]
- triglyceride homeostasis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID