BAIT
FAM160A1
family with sequence similarity 160, member A1
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
KIF5A
D12S1889, MY050, NKHC, SPG10
kinesin family member 5A
GO Process (9)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- axon guidance [IBA]
- blood coagulation [TAS]
- cytoskeleton-dependent intracellular transport [IBA]
- metabolic process [IBA, TAS]
- microtubule-based movement [IBA, TAS]
- protein localization [IBA]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.
In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins. While ~40 kinesins transport cargo toward the plus end of microtubules, a single dynein moves cargo in the opposite direction. How dynein transports a wide variety of cargos remains an open question. The FTS-Hook-FHIP ('FHF') cargo ... [more]
Elife Dec. 09, 2020; 10(); [Pubmed: 34882091]
Throughput
- High Throughput
Curated By
- BioGRID